The Resident Evil games are known for incorporating some challenging puzzles to keep players on their toes. Resident Evil Requiem is no different in this regard, as the initial Care Center section has multiple puzzles that players must solve. It also has multiple optional puzzles that can make things a little confusing. Fortunately, just knowing the solutions can make every puzzle a breeze.
Up to 12% off on LootBar Game Key.
Instant Delivery for Non-Stop Gaming.
Trusted 4.9/5 on Trustpilot, 10/10 among Players.
Official Partnership Route, Safe and reliable
All puzzle box solutions in Resident Evil Requiem
The puzzle box solutions are mandatory for Grace to solve. Every puzzle gives players one type of Quartz, and three of them are required to open the door that you can use to leave the Care Center. Of course, this does require some knowledge of what’s going on in the game’s story, so you can buy the game from a platform such as LootBar if you find yourself confused.
In total, there are three puzzle boxes that you have to open. You can find the solutions for the first two by looking at clues from nearby pictures. However, if you want to streamline the puzzles, then below are the solutions for the puzzle boxes.
Chairman’s Office puzzle box - Moon > Sun > Star > Moon
Lead Researcher’s Office puzzle box - Star > Sun > Moon > Sun
The third puzzle box is found in the Security Manager’s Office. You can’t solve this one, as you have to bring Emily to it. This is because this puzzle is in Braille, which Grace doesn’t know. Just interact with the nearby notebook on the table and then the puzzle box, giving you the level 3 wristband.
Organ Transport Box solution in Resident Evil Requiem
The Organ Transport Box is a mandatory puzzle that you must solve to get your hands on a frozen heart. This puzzle is found in the garage area, which you can reach after obtaining the level 1 wristband. You need to solve a small puzzle before opening the box. While the solution for this can be found inside the puzzle box found in the Lead Researcher’s Office, you can just open it immediately by using the solution below:
Examine the box from your inventory
Turn the box and click on the back panel
Set the bottom right option to HAND
Ensure the slider on the right is set in the middle
Press the fifth button
Press the second button
Set the bottom right option to AUTO again
This will open the organ box, letting you access the organ inside.
All Blood Specimen solutions in Resident Evil Requiem
Blood Specimen puzzles are handy for unlocking new crafting recipes for Grace to use. This is limited to the Care Center, though you can use it any time you can access the Blood Lab.
For this, you want to find the blood sample, and then take it to the Blood Lab and solve a small puzzle to get the connected crafting recipe.
The first blood sample is found in the Blood Lab itself. Take it to the machine and click the second square from the left once to solve the puzzle and get the crafting recipe for Handgun Ammo and Hemolytic Injectors.
The second blood sample is found in the Ward Office in the East Wing. This is found in the Records Room instead if you’re playing on Insanity. Solving this puzzle is easy, since you just have to press the middle cube once, then the second cube from the bottom. This will unlock the recipes for Med Injectors and 12.7x55mm Ammo.
The third blood sample is located in the Blood Lab, through the door that needs a level 1 wristband to be unlocked. The way to fix this one is to first pick the middle cube, and then the two corner cubes that aren't touching the center cube. In the end, press the cube in the middle of the three cubes that still have to be altered to complete the puzzle and unlock the capability to make Steroids and Stabilizers.
The last blood sample is locked to Insanity mode only. The last blood sample is found in the closet behindthe Waiting Room. After figuring this one out, you have to click the middle-left cube first, then the middle-right one, and lastly, the middle-bottom one. This will give you the ability to make the R.I.P Knife.
All safe codes in Resident Evil Requiem
Of course, it can’t be a Resident Evil game without a couple of safes that you have to crack. While you can find the codes for every safe in the game in different locations, you can just open them immediately by inputting the right solutions. Every safe is in the Care Center.
The first safe is found in the Bar & Lounge area. This safe’s code is:
Left 10 > Right 80 > Left 30
If on insanity difficulty, the code is: Right 20 > Left 50 > Right 30
The second safe is in the Examination Room. The code is:
Right 30 > Left 10 > Right 50
If on insanity difficulty, the code is: Left 50 > Right 30 > Left 90
There’s also a safe in the basement that you can open. To open this, input this code:
Right 60 > Left 40 > Right 80
On insanity, the code is: Left 70 > Right 50 > Left 20
The Sterilization Chamber holds a safe that some find confusing to open. Luckily, you can just enter this:
Right 10 > Left 90 > Right 20
On insanity, the code is: Left 80 > Right 50 > Left 0
Finally, you’ll find a safe in the Monitor Control Room. The code is:
Left 50 > Right 60 > Left 80
On insanity, the code is: Right 20 > Left 0 > Right 70
How to solve the VIP Suite double helix puzzle in Resident Evil Requiem
The VIP Suite in the Care Center’s courtyard has a mandatory puzzle that you must solve to go to the hidden basement area. While you can interact with multiple things here, you just want to interact with the wine bottle that’s near the entrance. Rotate it to reveal a Helix part inside, and then insert that on the lectern to solve this puzzle.
Conclusion
Every puzzle in Resident Evil Requiem is perfectly crafted to challenge players. Most of them just need you to have a sharp eye, but some also test your critical thinking skills. If you aren’t accustomed to Resident Evil’s unique way of setting out puzzles, then it may be a good idea to buy a Resident Evil Requiem Steam key to change that.
