Last Asylum: Plague is the unforgiving world that brings no excuses. So your success as a Plague Doctor in there totally depends entirely on the survivors you recruit to defend your sanctuary. Having an aggressive gameplay to deal with, knowing which heroes to invest your precious resources into is the difference between a thriving run and a fallen ruin. So, here is our Last Asylum: Plague tier list where we have ranked all heroes by their power as well as for their usefulness. So you will finally learn who makes it to the best power.
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Last Asylum: Plague Tier List
Last Asylum: Plague Tier List Overview
Before we dive into the exact hero specifics, let’s see how each of the Last Asylum: Plague heroes are being ranked:
| Tier | Hero Names | Power Level & Role |
| SS | Arthur, Marlena | Game-Breakers: Essential for end-game content and high-level PvP. |
| S | Grifith, Grenwald, Bella | Top Tier: Highly reliable and capable of carrying through most chapters. |
| A | Hastar, Stellar, Claire, Bestar | Strong Picks: Great for niche roles or as primary heroes for F2P players. |
| B | Sivir, Celia, Kesso, Lucius | Situational: Useful in the early-to-mid game but fall off later. |
| C | Ash | Underwhelming: Requires too much investment for low returns. |
| D | Kafa, William, Robin, Durant | Avoid: Only use if you have no other options. |
SS-Tier: The Apex Survivors
Arthur (Tank): Arthur is arguably the most important hero you see among the Last Asylum: Plague characters. He has an ability to generate team-wide shields and can mitigate massive amounts of damage so Arthur is generally turning himself into the undisputed king of the frontline. If you are facing the Rat King or competing in Alliance Warfare, Arthur ensures your squishy damage dealers stay alive.
Arthur
Marlena (DPS): If Arthur is the ultimate shield in this Last Asylum: Plague tier list, Marlena can be called the ultimate sword. She possesses the highest single-target burst damage and Marlena got some skills scale exceptionally well with investment. So yes, she can be your primary choice for deleting bosses before they can overwhelm your formation.
Marlena
Note: If you are trying to reach the peak of competitive play, you can look to maximize these SS-tier units quickly. Utilizing LootBar to top up Last Asylum: Plague is a highly effective way to secure the resources needed for these top-tier pulls, allowing you to bypass the slow grind and fortify your sanctuary with Arthur and Marlena much faster.
S-Tier: The Reliable Powerhouses
Grifith: Grifith is a specialist in monster damage reduction. His "Spirit Snake" is an ability that will act as a literal lifesaver during Rat Swarm waves, and it is also significantly lowering the pressure on your healers.
Grifith
Grenwald: If you are looking for the definition of a "Glass Cannon”, it is literally Grenwald. While his defense is low, Grenwald comes with a raw attack power that is rivaled only by Marlena. You can pair him with Arthur to keep him safe while he shreds enemy lines.
Grenwald
Bella: The best alternative to Arthur from the S tier is Bella. She is a durable SSR tank who provides solid crowd control and personal survivability, and Bella is an excellent anchor for your second squad.
Bella
A-Tier: Strategic Specialists
Stellar: Stellar is one of the few dedicated supports from the Last Asylum: Plague tier list and her ultimate buffs team damage against monsters. Stellar’s passive provides a clutch heal to the lowest HP ally upon her death.
Stellar
Claire: Claire comes as a single-target specialist who excels in boss-heavy stages. Her passive also boosts the damage of your three highest-attack warriors, and is providing great team-wide utility.
Claire
Hastar & Bestar: These heroes excel in "Reclamation" modes where sustained damage and debuffs (like Bleed) are more effective than raw burst.
Hastar & Bestar
Remember that building a balanced team of S and A-tier heroes requires a steady stream of upgrade materials and hero shards. So now you can use LootBar to get the best deals on in-game currency, because they got Diamond reserves necessary to participate in limited-time recruitment events for these essential characters.
LootBar
B-Tier and Below: The Early Game Transition
Characters like Sivir, Celia, and Lucius are excellent for clearing the first few chapters of the main quest. However, when you approach the mid-game (Level 40+), you will find their stats cannot keep up with the rising difficulty of the pandemic.
Ash (C-Tier) and the D-Tier heroes like Kafa, William, Robin, Durant should generally be left at low levels. It is better to save your gold and EXP materials for heroes that appear higher on this list so you can easily have a long-term progression that isn't stalled by "resource waste."
Conclusion
With that, we have come to an end to our Last Asylum: Plague tier list. Please make sure that you are always getting an SS or S tier because they can guarantee you a win. And the more you invest in them, the more you will find it rewarding.
